CACYBP Antikörper (AA 1-185)
Kurzübersicht für CACYBP Antikörper (AA 1-185) (ABIN5775925)
Target
Alle CACYBP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-185
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Verwendungszweck
- Human CACYBP antibody
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Aufreinigung
- Purified
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Immunogen
- Recombinant human CACYBP (1-185aa) purified from E. coli
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Isotyp
- IgG2a kappa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing cycles
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- CACYBP (Calcyclin Binding Protein (CACYBP))
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Andere Bezeichnung
- CACYBP
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Hintergrund
- CACYBP (Calcyclin-binding protein) is primarily a nuclear protein that contains one CS domain and one SGS domain. CACYBP is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in ubiquitin E3 complexes. It also participates in the ubiquitin-mediated degradation of b-catenin. CACYBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on b-catenin protein expression and transcriptional activation of TCF/LEF.
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NCBI Accession
- NP_001007215
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Pathways
- Response to Growth Hormone Stimulus
Target
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