Aminoacylase 1 Antikörper (AA 1-408)

Produktnummer ABIN5775904

Der Maus Monoklonal Anti-Aminoacylase 1-Antikörper wurde für WB, ELISA, FACS, IF und ICC validiert. Er ist geeignet, Aminoacylase 1 in Proben von Human zu detektieren.

Kurzübersicht für Aminoacylase 1 Antikörper (AA 1-408) (ABIN5775904)

Target: Aminoacylase 1 (ACY1)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Aminoacylase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: AT1E2

Produktdetails anti-Aminoacylase 1 Antikörper

Bindungsspezifität: AA 1-408

Immunogen: Recombinant human ACY1 (1-408aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu Aminoacylase 1

Target: Aminoacylase 1 (ACY1)

Andere Bezeichnung: Aminoacylase/ACY1

Hintergrund: Aminoacylase-1, also designated N-acyl-L-amino-acid amidohydrolase or ACY1, is a member of the largest metallopeptidase family called M20A. Aminoacylase-1 is a zinc-binding homodimeric enzyme expressed in kidney, brain, placenta and spleen. It is the most abundant of the aminoacylases. Defects in ACY1 are the cause of aminoacylase-1 deficiency (ACY1D). ACY1D results in a metabolic disorder manifesting with encephalopathy, unspecific psychomotor delay, psychomotor delay with atrophy of the vermis and syringomyelia, marked muscular hypotonia or normal clinical features. All affected individuals exhibit markedly increased urinary excretion of several N-acetylated amino acids.

NCBI Accession: NP_000657