VCctxB (Subunit beta) Antikörper

Produktnummer ABIN576688

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch VCctxB in ELISA und IP. Es zeigt Reaktivität gegenüber Proben von Vibrio cholerae.

Kurzübersicht für VCctxB (Subunit beta) Antikörper (ABIN576688)

Target: VCctxB

Reaktivität: Vibrio cholerae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: ELISA, Immunoprecipitation (IP)

Produktdetails

Bindungsspezifität: Subunit beta

Spezifität: Recognizes the beta subunit of cholera toxin. The beta subunit of cholera toxin binds to a GM1-ganglioside receptor which is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin alpha subunit into cells. The holotoxin consists of a pentameric ring of beta subunits whose central pore is occupied by the alpha subunit. The alpha subunit contains two chains, A1 and A2, linked by a disulfide bridge. The alpha subunit (and cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

Aufreinigung: Purified

Immunogen: Purified Choleragenoid.

Type of Immunogen: Purified protein

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Target Species of Antibody: Vibrio cholerae

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Short term: -20°C
Long term: -20°C.

Antigendetails

Target: VCctxB

Andere Bezeichnung: Cholera Toxin B Subunit

Hintergrund: Name/Gene ID: VC1456
Family: Virulence Factor

Synonyms: VC1456, VCctxB

Gen-ID: 2613962