GABBR1 Antikörper (AA 947-961)

Produktnummer ABIN574068

Produktdetails anti-GABBR1 Antikörper

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Bindungsspezifität: AA 947-961

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Affe, Schwein, Hamster, Hund, Pferd, Kaninchen, Fledermaus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GABBR1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Marke: IHC-plus™

Spezifität: Human GABBR1. This antibody is expected to recognize reported isoforms a, b and c (NP_001461.1, NP_068703.1, NP_068704.2 resp.).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Pig (100%) Phytophthora (80%).

Aufreinigung: Immunoaffinity purified

Immunogen: Synthetic peptide DRLSCDGSRVHLLYK from the C-terminus of human GABBR1 (NP_001461.1, NP_068703.1, NP_068704.2, NP_068705.2). Percent identity by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Bovine, Dog, Bat, Horse, Rabbit, Pig (100%), Phytophthora (80%).

Type of Immunogen: Synthetic peptide

Anwendungsinformationen

Applikationshinweise: Approved: IHC, IHC-P (3.75 - 5 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 to 5 μg/mL.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu GABBR1

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Andere Bezeichnung: GABABR1 / GABBR1 (GABBR1 Produkte)

Synonyme: GABABR1 antikoerper, GABBR1-3 antikoerper, GB1 antikoerper, GPRC3A antikoerper, dJ271M21.1.1 antikoerper, dJ271M21.1.2 antikoerper, gabbr1 antikoerper, GABBR1 antikoerper, GABA(B)R1 antikoerper, GABAB1 antikoerper, GABAbR1 antikoerper, bM573K1.1 antikoerper, gamma-aminobutyric acid type B receptor subunit 1 antikoerper, gamma-aminobutyric acid (GABA) B receptor, 1a antikoerper, gamma-aminobutyric acid (GABA) B receptor, 1 antikoerper, GABBR1 antikoerper, gabbr1a antikoerper, gabbr1 antikoerper, Gabbr1 antikoerper

Hintergrund: Name/Gene ID: GABBR1
Subfamily: GABA(B)
Family: GPCR

Synonyms: GABBR1, DJ271M21.1.1, DJ271M21.1.2, GABA(B) receptor, Gaba-b-r1a, GABA-BR1, Gaba-br1a receptor, GABAB, subunit 1c, GABAB1, GABA-B receptor 1, Gaba-b1, Gababr1 receptor, GPRC3A, Gabab-receptor subunit 1a, GABABR1, GABBR1-3, GBR1, HGB1a, GABA-B-R1, GB1

Gen-ID: 2550

NCBI Accession: NP_001461, NP_068703, NP_068704, NP_068705

UniProt: Q9UBS5

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process