S100A7 Antikörper

Produktnummer ABIN5708274

Der Kaninchen-Polyklonal Anti-S100A7-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet zum Nachweis von S100A7 in Proben aus Human, Maus und Ratte. }

Kurzübersicht für S100A7 Antikörper (ABIN5708274)

Target: S100A7 (S100 Calcium Binding Protein A7 (S100A7))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser S100A7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-S100A7 Antikörper

Aufreinigung: Antigen affinity purified

Immunogen: A recombinant human partial protein corresponding to amino acids S2-Q101 was used as the immunogen for the Psoriasin antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Psoriasin antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Psoriasin antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu S100A7

Target: S100A7 (S100 Calcium Binding Protein A7 (S100A7))

Andere Bezeichnung: S100A7 / Psoriasin

Hintergrund: S100 calcium-binding protein A7 (S100A7), also known as psoriasin, is a protein that in humans is encoded by the S100A7 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.

UniProt: P31151

Pathways: S100 Proteine