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ADA Antikörper (AA 2-238)

Der Kaninchen Polyklonal Anti-ADA-Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, ADA in Proben von Maus und Ratte zu detektieren.
Produktnummer ABIN5708187

Kurzübersicht für ADA Antikörper (AA 2-238) (ABIN5708187)

Target

Alle ADA Antikörper anzeigen
ADA (Adenosine Deaminase (ADA))

Reaktivität

  • 66
  • 34
  • 18
  • 14
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Maus, Ratte

Wirt

  • 75
  • 20
  • 1
Kaninchen

Klonalität

  • 77
  • 19
Polyklonal

Konjugat

  • 52
  • 8
  • 6
  • 6
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ADA Antikörper ist unkonjugiert

Applikation

  • 85
  • 41
  • 15
  • 15
  • 13
  • 13
  • 13
  • 12
  • 9
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 15
    • 9
    • 8
    • 8
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-238

    Aufreinigung

    Antigen affinity purified

    Immunogen

    A recombinant mouse partial protein corresponding to amino acids A2-H238 was used as the immunogen for the ADA antibody.

    Isotyp

    IgG
  • Applikationshinweise

    Optimal dilution of the ADA antibody should be determined by the researcher.\. Western Blot: 0.5-1 μg/mL,IHC (FFPE): 1-2 μg/mL,Direct ELISA: 0.1-0.5 μg/mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    Lagerung

    -20 °C

    Informationen zur Lagerung

    After reconstitution, the ADA antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target

    ADA (Adenosine Deaminase (ADA))

    Andere Bezeichnung

    ADA / Adenosine deaminase

    Hintergrund

    Adenosine Deaminase (also known as Adenosine aminohydrolase, or ADA) is an enzyme involved in purine metabolism. Primarily, ADA in humans is involved in the development and maintenance of the immune system. However, ADA association has also been observed with epithelial cell differentiation, neurotransmission, and gestation maintenance. It has also been proposed that ADA, in addition to adenosine breakdown, stimulates release of excitatory amino acids and is necessary to the coupling of A1 adenosine receptors and heterotrimeric G proteins. Adenosine deaminase deficiency leads to pulmonary fibrosis, suggesting that chronic exposure to high levels of adenosine can exacerbate inflammation responses rather than suppressing them. It has also been recognized that adenosine deaminase protein and activity is upregulated in mouse hearts that overexpress HIF-1 alpha, which in part explains the attenuated levels of adenosine in HIF-1 alpha expressing hearts during ischemic stress.

    UniProt

    P03958

    Pathways

    Regulation of G-Protein Coupled Receptor Protein Signaling, Ribonucleoside Biosynthetic Process
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