KRT16 Antikörper (C-Term)

Produktnummer ABIN5707759

Dieses Anti-KRT16-Antikörper ist ein Kaninchen Monoklonal-Antikörper zur Detektion von KRT16 in IHC (p). Geeignet für Human.

Kurzübersicht für KRT16 Antikörper (C-Term) (ABIN5707759)

Target: KRT16 (Keratin 16 (KRT16))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser KRT16 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: KRT16-2043R

Produktdetails anti-KRT16 Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Reinheit: Protein A affinity chromatography

Immunogen: A C-terminal region peptide was used as the immunogen for the recombinant Keratin 16 antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant Keratin 16 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant Keratin 16 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu KRT16

Target: KRT16 (Keratin 16 (KRT16))

Andere Bezeichnung: KRT16 / Cytokeratin 16

Hintergrund: Cytokeratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I Cytokeratins (Cytokeratins 9 to 23) and one type II Cytokeratins (keratins 1 to 8). The cytokeratin proteins play a critical role in differentiation, as well as tissue specialization and function, to maintain the overall structural integrity of epithelial cells. Cytokeratins are also useful markers in identifying the origin of metastatic tumors. Cytokeratin 16 is expressed in benign stratified squamous epithelium and squamous cell carcinoma of the head and neck, as well as luminal cells of mammary gland and sweat ducts. It is absent in non-invasive breast carcinomas and normal breast tissue.