Human Papilloma Virus 16 Capsid Protein (HPV-16 L1) Antikörper

Produktnummer ABIN5707604

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Human Papilloma Virus 16 Capsid Protein in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human Papillomavirus 16 (HPV-16).

Kurzübersicht für Human Papilloma Virus 16 Capsid Protein (HPV-16 L1) Antikörper (ABIN5707604)

Target: Human Papilloma Virus 16 Capsid Protein (HPV-16 L1)

Reaktivität: Human Papillomavirus 16 (HPV-16)

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: HPV16-2058R

Produktdetails

Aufreinigung: Purified

Reinheit: Protein A affinity chromatography

Immunogen: Human papilloma virus type 16, major capsid protein L1, was used as the immunogen for the recombinant HPV16 L1 antibody.

Isotyp: IgG kappa

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the recombinant HPV16 L1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT,Prediluted IHC only format : incubate for 30 min at RT (1)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the recombinant HPV16 L1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Antigendetails

Target: Human Papilloma Virus 16 Capsid Protein (HPV-16 L1)

Andere Bezeichnung: HPV-16 L1

Substanzklasse: Viral Protein

Hintergrund: Reacts with a protein of 57  kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16). It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33, very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.