ACSS2 Antikörper (N-Term)

Produktnummer ABIN5706867

Produktdetails anti-ACSS2 Antikörper

Target: ACSS2 (Acyl-CoA Synthetase Short-Chain Family Member 2 (ACSS2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACSS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktmerkmale:

Synonyms: rabbit anti-ACSS2, rabbit anti ACSS2, Acetyl-coenzyme A synthetase (cytoplasmic), Acetate-CoA ligase, Acetyl-CoA synthetase, ACS, AceCS, Acyl-CoA synthetase short-chain family member 2, Acyl-activating enzyme, ACSS2, ACAS2

Background: This antibody is designed, produced, and validated as part of a collaboration between Rockland and the National Cancer Institute (NCI). ACSS2 (Acyl-CoA synthetase short-chain family member 2) is a protein coding gene encoding a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. This protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP. Expression of this gene is regulated by sterol regulatory element-binding proteins, transcription factors that activate genes required for the synthesis of cholesterol and unsaturated fatty acids. This protein is upregulated in many cancers and is important for pro-survival under hypoxic conditions. ACSS2 may be associated with disorders such as Cystoisosporiasis. Anti-ACSS2 Antibody is useful for researchers interested in parasites, intestines, Glucose Energy Metabolism, and AKT research.

Gene Name: ACSS2

Aufreinigung: This affinity purified antibody is directed against human ACSS2 protein. Anti-ACSS2 Antibody to was affinity purified from monospecific antiserum by immunoaffinity chromatography. Blast analysis of the sequence of the immunogen shows 100% identity with human and 80% identity to mouse.

Immunogen:

Immunogen: ACSS2 affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with synthetic peptide near the N-term of human ACSS2.

Immunogen Type: Peptide

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-ACSS2 Antibody has been tested in Western Blot and ELISA. Expect a band at approximately 76 kDa in western blot using appropriate lysates. Positive control whole cell lysates used Hep-G2 at 1 μg/mL for WB. Although not tested, this antibody is likely functional in immunohistochemistry, immunofluorescence, and immunoprecipitation.

Western Blot Dilution: 1.0 μg/mL

ELISA Dilution: 1:10,000-1:50,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.01 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride,  pH 7.2

Stabilizer: None

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Haltbarkeit: 12 months

Details zu ACSS2

Target: ACSS2 (Acyl-CoA Synthetase Short-Chain Family Member 2 (ACSS2))

Andere Bezeichnung: ACSS2 (ACSS2 Produkte)

Synonyme: zgc:92200 antikoerper, wu:fa04c03 antikoerper, wu:fj80b06 antikoerper, wu:fj80h04 antikoerper, ACAS2 antikoerper, ACECS antikoerper, ACS antikoerper, ACSA antikoerper, dJ1161H23.1 antikoerper, 1110017C11Rik antikoerper, ACAS antikoerper, Acas1 antikoerper, Acas2 antikoerper, AceCS1 antikoerper, Acs1 antikoerper, acyl-CoA synthetase short chain family member 2 antikoerper, acetyl-coenzyme A synthetase, cytoplasmic antikoerper, acyl-CoA synthetase short-chain family member 2 antikoerper, acyl-CoA synthetase short chain family member 1 antikoerper, ACSS2 antikoerper, LOC100179555 antikoerper, LOC100211402 antikoerper, acss2 antikoerper, ACSS1 antikoerper, Acss2 antikoerper

Gen-ID: 55902

NCBI Accession: NP_001070020

UniProt: Q9NR19