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Ngp Antikörper

This anti-Ngp antibody (ABIN5706813) is a Rabbit Polyclonal antibody detecting Ngp in FM, IF, WB. Suitable for Mouse.
Rockland
Produktnummer ABIN5706813
Hersteller Produkt- Nr.: 600-401-gw9

Kurzübersicht für Ngp Antikörper (ABIN5706813)

Target

Ngp (NGP) (Neutrophilic Granule Protein (NGP))

Reaktivität

Maus

Wirt

Kaninchen

Klonalität

Polyklonal

Applikation

Fluorescence Microscopy (FM), Immunofluorescence (IF), Western Blotting (WB)
  • Hersteller Produkt- Nr.

    600-401-gw9

    Hersteller

    Rockland

    Verwendungszweck

    Ngp Antibody

    Kreuzreaktivität (Details)

    Anti-NGP is directed against full-length mouse NGP.

    Produktmerkmale

    Synonyms: rabbit anti-NGP antibody, Neutrophilic granule protein, Cystatin-like protein, Myeloid bactenecin protein, Myeloid secondary granule protein

    Aufreinigung

    This product is an affinity purified antibody produced by immunoaffinity chromatography using recombinant protein coupled to agarose beads.

    Sterilität

    Sterile filtered

    Immunogen

    Immunogen: Affinity purified Anti-NGP antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein of mouse NGP protein.

    Immunogen Type: Recombinant Protein

    Isotyp

    IgG
  • Applikationshinweise

    Application Note: This affinity purified antibody has been tested for use in IF, and western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a band 39-42 kDa for non reduced and 20-27 kDa for reduced gels corresponding to NGP by western blotting in the appropriate cell lysate or extract. 

    Western Blot Dilution: 1:1000

    IF Microscopy Dilution: 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1.1 mg/mL

    Buffer

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    Stabilizer: None

    Preservative: 0.01 % (w/v) Sodium Azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store vial at -20° C prior to opening.  Aliquot contents and freeze at -20° C or below for extended storage.  Avoid cycles of freezing and thawing.  Centrifuge product if not completely clear after standing at room temperature.  This product is stable for several weeks at 4° C as an undiluted liquid.  Dilute only prior to immediate use.

    Haltbarkeit

    12 months
  • Hong, Qu, Wuest, Huang, Huang, Lin: "Neutrophilic Granule Protein Is a Novel Murine LPS Antagonist." in: Immune network, Vol. 19, Issue 5, pp. e34, (2019) (PubMed).

  • Target

    Ngp (NGP) (Neutrophilic Granule Protein (NGP))

    Andere Bezeichnung

    Ngp

    Hintergrund

    Background: This antibody is designed, produced, and validated as part of a collaboration with the National Cancer Institute (NCI). A proteomic study in 2011 determined a direct correlation between NGP mRNA levels and myeloid-derived suppressor cells. Specifically cathepsin B, a catalytic mechanism and potentially biomarker in a variety of cancers and amyloid plaque development, was inhibited by NGP. The significance of NGP as a negative regulator of tumor metastasis makes this antibody ideal for investigators involved in cancer research, as well as Alzheimer's research.

    Gen-ID

    18054

    NCBI Accession

    NP_032720
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