HBd Antikörper (N-Term)

Produktnummer ABIN5706735

Hersteller Produkt- Nr.: 200-301-gs8

Dieses Anti-HBd-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von HBd in ELISA und WB. Geeignet für Human.

Kurzübersicht für HBd Antikörper (N-Term) (ABIN5706735)

Target: HBd (Hemoglobin, delta (HBd))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HBd Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Klon: 21G1-F1-B9-G9-D11

Produktdetails anti-HBd Antikörper

Bindungsspezifität: N-Term

Hersteller Produkt- Nr.: 200-301-gs8

Hersteller: Rockland

Verwendungszweck: Hemoglobin beta A-2 Antibody

Kreuzreaktivität (Details): This protein A purified mouse monoclonal antibody reacts specifically with human HbA-2 delta isoform.

Produktmerkmale: Synonyms: mouse anti-HbA-2 antibody, mouse anti-hemoglobin antibody, Hemoglobin Subunit Delta, Hemoglobin Delta Chain 4, Delta-Globin 4, HbD, HbA-2 Antibody, Sickle Cell Disease (SCD)

Aufreinigung: Anti-HbA-2 is purified from tissue culture supernatant by protein A purification.

Sterilität: Sterile filtered

Immunogen:

Immunogen: Anti-Hemoglobin beta A-2 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus of Hb delta-subunit conjugated to KLH.

Immunogen Type: Conjugated Peptide

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

Application Note: Anti-Hemoglobin beta A-2 (MOUSE) antibody has been tested by ELISA and Western Blotting. This antibody is designed for use in lateral flow. Specific conditions of reactivity should be optimized by the end user. Expect a band of approximately 16 kDa.

Western Blot Dilution: 1 μg/mL

ELISA Dilution: 1:20,000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.00 mg/mL

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store vial at -20° C prior to opening. This product is stable at 4° C as an undiluted liquid. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Dilute only prior to immediate use.

Haltbarkeit: 12 months

Details zu HBd

Target: HBd (Hemoglobin, delta (HBd))

Andere Bezeichnung: HBD

Hintergrund: Background: HbA-2 or hemoglobin delta subunit antibodies detect the delta-specific sequence in the hemoglobin delta-subunit found in HbA-2. Functional hemoglobin (Hb) is a hetero tetramer and the dominant form of Adult Hb is composed of 2 alpha and 2 beta subunits (α2β2). Hemoglobin A-2 (HbA-2) is a normal but minor variant of hemoglobin A that consists of two alpha and two delta chains (α2δ2). Hemoglobin A-2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene, and HbA2 is also linked to neurological disorders. HbA-2 form exists in small amounts in all adult humans (1.5-3.1 % of all hemoglobin molecules) and is increased in people with Sickle-cell disease. Its normal biological role is not well understood. HbA-2 antibody does not react other forms of Hb including no cross-reaction to HbA or beta subunit. This antibody is ideal for investigators involved in Cardiovascular and developmental biology research.

Gen-ID: 3045

NCBI Accession: NP_000510

UniProt: P02042