MBNL3 Antikörper

Produktnummer ABIN5705442

Produktdetails anti-MBNL3 Antikörper

Target: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBNL3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Immunogen: muscleblind-like 3 (Drosophila)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab05041( MBNL3 Antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu MBNL3

Target: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Andere Bezeichnung: MBNL3 (MBNL3 Produkte)

Synonyme: A530038J18Rik antikoerper, AI661274 antikoerper, CHCR antikoerper, E430034C16Rik antikoerper, MBLX antikoerper, MBLX39 antikoerper, MBXL antikoerper, mbxl antikoerper, RGD1565834 antikoerper, muscleblind like splicing regulator 3 antikoerper, muscleblind like splicing factor 3 antikoerper, Muscleblind-like protein 3-like antikoerper, muscleblind-like splicing regulator 3 antikoerper, MBNL3 antikoerper, Mbnl3 antikoerper, mbnl3 antikoerper

Hintergrund: Synonyms:CHCR, MBLX39, MBXL Background:Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T(TNNT2) pre-mRNA exon inclusion but induces insulin receptor(IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology(DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.

Molekulargewicht: 38 kDa

Gen-ID: 55796

UniProt: Q9NUK0

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development