MBNL3 Antikörper

Produktnummer ABIN5705442

Dieser Anti-MBNL3 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von MBNL3 in ELISA, WB und IHC. Geeignet für Human und Maus.

Kurzübersicht für MBNL3 Antikörper (ABIN5705442)

Target: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MBNL3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MBNL3 Antikörper

Verwendungszweck: MBNL3 antibody

Immunogen: muscleblind-like 3 (Drosophila)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab05041( MBNL3 Antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu MBNL3

Target: MBNL3 (Muscleblind-Like Splicing Regulator 3 (MBNL3))

Andere Bezeichnung: MBNL3

Hintergrund:

Synonyms: Muscleblind-like protein 3|Cys3His CCG1-required protein|Muscleblind-like X-linked protein|Protein HCHCR|MBNL3|CHCR|MBLX39|MBXL

Background: Mediates pre-mRNA alternative splicing regulation. Acts either as activator or repressor of splicing on specific pre-mRNA targets. Inhibits cardiac troponin-T(TNNT2) pre-mRNA exon inclusion but induces insulin receptor(IR) pre-mRNA exon inclusion in muscle. Antagonizes the alternative splicing activity pattern of CELF proteins. May play a role in myotonic dystrophy pathophysiology(DM). Could inhibit terminal muscle differentiation, acting at approximately the time of myogenin induction.

Molekulargewicht: 38 kDa

Gen-ID: 55796

UniProt: Q9NUK0

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development