PEX5 Antikörper

Produktnummer ABIN5704976

Der Kaninchen-Polyklonal Anti-PEX5-Antikörper wurde für WB, ELISA, IHC und IP validiert. Er ist geeignet zum Nachweis von PEX5 in Proben aus Human, Maus und Ratte. }

Kurzübersicht für PEX5 Antikörper (ABIN5704976)

Target: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEX5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-PEX5 Antikörper

Verwendungszweck: PEX5 antibody

Immunogen: peroxisomal biogenesis factor 5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:500-1:5000 IP : 1:200-1:2000 IHC : 1:100-1:400 IF : 1:50-1:500

Kommentare:

human brain tissue were subjected to SDS PAGE followed by western blot with FNab06331(PEX5 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu PEX5

Target: PEX5 (Peroxisomal Biogenesis Factor 5 (PEX5))

Andere Bezeichnung: PEX5

Hintergrund:

Synonyms: Peroxisomal targeting signal 1 receptor (PTS1 receptor, PTS1R)|PTS1-BP|Peroxin-5|Peroxisomal C-terminal targeting signal import receptor|Peroxisome receptor 1|PEX5|PXR1

Background: The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified.

Molekulargewicht: 70 kDa

Gen-ID: 5830

UniProt: P50542

Pathways: Monocarboxylic Acid Catabolic Process