PHKG2 Antikörper

Produktnummer ABIN5704140

Dieses Anti-PHKG2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PHKG2 in WB, IHC, ELISA und IF. Geeignet für Human, Maus und Ratte.

Kurzübersicht für PHKG2 Antikörper (ABIN5704140)

Target: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHKG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-PHKG2 Antikörper

Immunogen: phosphorylase kinase, gamma 2 (testis)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab06395(PHKG2 antibody) at dilution of 1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu PHKG2

Target: PHKG2 (phosphorylase Kinase, gamma 2 (Testis) (PHKG2))

Andere Bezeichnung: PHKG2

Hintergrund: Synonyms: Background:Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, encoded by two different genes. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, and the hepatic isoform is encoded by this gene. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9C, also known as autosomal liver glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Gen-ID: 5261

UniProt: P15735

Pathways: Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process