TIA1 Antikörper

Produktnummer ABIN5704065

Dieses Anti-TIA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TIA1 in WB, ELISA und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für TIA1 Antikörper (ABIN5704065)

Target: TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Produktdetails anti-TIA1 Antikörper

Verwendungszweck: TIA1 antibody

Immunogen: TIA1 cytotoxic granule-associated RNA binding protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu TIA1

Target: TIA1 (TIA1 Cytotoxic Granule-Associated RNA Binding Protein (TIA1))

Andere Bezeichnung: TIA1

Hintergrund:

Synonyms: Cytotoxic granule associated RNA binding protein TIA1|Nucleolysin TIA-1 isoform p40|RNA-binding protein TIA-1|T-cell-restricted intracellular antigen-1 (TIA-1)|p40-TIA-1|TIA1

Background: The product encoded by this gene is a member of a RNA-binding protein family and possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. It has been suggested that this protein may be involved in the induction of apoptosis as it preferentially recognizes poly(A) homopolymers and induces DNA fragmentation in CTL targets. The major granule-associated species is a 15- kDa protein that is thought to be derived from the carboxyl terminus of the 40- kDa product by proteolytic processing. Alternative splicing resulting in different isoforms of this gene product has been described in the literature.

Gen-ID: 7072

UniProt: P31483