MMP1 Antikörper

Produktnummer ABIN5703938

Der Kaninchen Polyklonal Anti-MMP1-Antikörper wurde für WB, IHC, ELISA, IF, IP und FACS validiert. Er ist geeignet, MMP1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für MMP1 Antikörper (ABIN5703938)

Target: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)

Produktdetails anti-MMP1 Antikörper

Verwendungszweck: MMP1 antibody

Immunogen:

Immunogen sequence: 23- 215aa

Immunogen: matrix metallopeptidase 1 (interstitial collagenase)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:200-1:2000 IP :1:500-1:5000 IHC : 1:100-1:400 IF : 1:20-1:200

Kommentare:

A549 cells were subjected to SDS PAGE followed by western blot with FNab05233(MMP1 antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu MMP1

Target: MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))

Andere Bezeichnung: MMP1

Hintergrund:

Synonyms: Interstitial collagenase|Fibroblast collagenase|Matrix metalloproteinase-1 (MMP-1)|22 kDa interstitial collagenase|27 kDa interstitial collagenase|MMP1|CLG

Background: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Molekulargewicht: 54 kDa,62 kDa

Gen-ID: 4312

UniProt: P03956