CHMP1B Antikörper

Produktnummer ABIN5703172

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CHMP1B in WB, IHC, ELISA und IP. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für CHMP1B Antikörper (ABIN5703172)

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CHMP1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Produktdetails anti-CHMP1B Antikörper

Verwendungszweck: CHMP1B antibody

Immunogen: chromatin modifying protein 1B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab01657(CHMP1B antibody) at dilution of 1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu CHMP1B

Target: CHMP1B (Charged Multivesicular Body Protein 1B (CHMP1B))

Andere Bezeichnung: CHMP1B

Hintergrund:

Synonyms: Charged multivesicular body protein 1b|CHMP1.5|Chromatin-modifying protein 1b (CHMP1b)|Vacuolar protein sorting-associated protein 46-2 (Vps46-2, hVps46-2)|CHMP1B|C18orf2

Background: CHMP1B belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).

Molekulargewicht: 28 kDa

Gen-ID: 57132

UniProt: Q7LBR1