PSMA6 Antikörper

Produktnummer ABIN5702617

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch PSMA6 in WB, IHC, IF, ELISA und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für PSMA6 Antikörper (ABIN5702617)

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PSMA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP)

Produktdetails anti-PSMA6 Antikörper

Verwendungszweck: PSMA6 antibody

Immunogen: proteasome (prosome, macropain) subunit, alpha type, 6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

MCF7 cells were subjected to SDS PAGE followed by western blot with FNab06865(PSMA6 antibody) at dilution of 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu PSMA6

Target: PSMA6 (Proteasome Subunit alpha 6 (PSMA6))

Andere Bezeichnung: PSMA6

Hintergrund:

Synonyms: Proteasome subunit alpha type-6|27 kDa prosomal protein (PROS-27, p27K)|Macropain iota chain|Multicatalytic endopeptidase complex iota chain|Proteasome iota chain|PSMA6|PROS27

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.

Gen-ID: 5687

UniProt: P60900

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA