STING1 (AA 170-379) Antikörper

Produktnummer ABIN5701799

Der Kaninchen Polyklonal Anti- Antikörper wurde für WB, IHC, ELISA, FACS, IF und IP validiert. Er ist geeignet, in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für STING1 (AA 170-379) Antikörper (ABIN5701799)

Target: STING1

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP)

Produktdetails

Bindungsspezifität: AA 170-379

Verwendungszweck: STING1 antibody

Immunogen:

Immunogen sequence: 170-379aa

Immunogen: transmembrane protein 173

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse thymus tissue were subjected to SDS PAGE followed by western blot with FNab08759(TMEM173 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Antigendetails

Target: STING1

Hintergrund:

Synonyms: Stimulator of interferon genes protein (hSTING)|Endoplasmic reticulum interferon stimulator (ERIS)|Mediator of IRF3 activation (hMITA)|Transmembrane protein 173|STING1|ERIS|MITA|STING|TMEM173

Background: This gene encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The encoded protein is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex. Mutations in this gene are the cause of infantile-onset STING-associated vasculopathy. Alternate splicing results in multiple transcript variants.

Gen-ID: 340061

UniProt: Q86WV6