PPARA Antikörper
Kurzübersicht für PPARA Antikörper (ABIN5701207)
Target
Alle PPARA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Immunogen
- peroxisome proliferator-activated receptor alpha
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Isotyp
- IgG
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Applikationshinweise
- WB : 1:200-1:1000 IP : 1:200-1:1000 IHC : 1:50-1:200
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Kommentare
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U-937 cells were subjected to SDS PAGE followed by western blot with FNab06663(PPARA antibody) at dilution of 1:300
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Haltbarkeit
- 12 months
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- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
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Andere Bezeichnung
- PPARA
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Hintergrund
- Synonyms:hPPAR, NR1C1, PPAR, PPAR alpha, PPARA Background:Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine(16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2.
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Molekulargewicht
- 52-55 kDa
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Gen-ID
- 5465
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UniProt
- Q07869
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Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
Target
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