MMP13 Antikörper

Produktnummer ABIN5701112

Der Kaninchen Polyklonal Anti-MMP13-Antikörper wurde für WB, IHC, ELISA und IF validiert. Er ist geeignet, MMP13 in Proben von Human, Maus, Ratte und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für MMP13 Antikörper (ABIN5701112)

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-MMP13 Antikörper

Immunogen: matrix metallopeptidase 13 (collagenase 3)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

MDA-MB-453s cells were subjected to SDS PAGE followed by western blot with FNab05235( MMP13 Antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu MMP13

Target: MMP13 (Matrix Metallopeptidase 13 (Collagenase 3) (MMP13))

Andere Bezeichnung: MMP13

Hintergrund: Synonyms:CLG3, Collagenase 3, Matrix metalloproteinase 13, MMP 13, MMP13 Background:Plays a role in the degradation of extracellular matrix proteins including fibrillar collagen, fibronectin, TNC and ACAN. Cleaves triple helical collagens, including type I, type II and type III collagen, but has the highest activity with soluble type II collagen. Can also degrade collagen type IV, type XIV and type X. May also function by activating or degrading key regulatory proteins, such as TGFB1 and CTGF. Plays a role in wound healing, tissue remodeling, cartilage degradation, bone development, bone mineralization and ossification. Plays a role in keratinocyte migration during wound healing. May play a role in cell migration and in tumor cell invasion.It can detect the glycosylated proMMP-13(70 kDa), unglycosylated proform(54 kDa).

Molekulargewicht: 50-52 kDa

Gen-ID: 4322

UniProt: P45452