BAIAP2 Antikörper

Produktnummer ABIN5700348

Der Kaninchen Polyklonal anti-BAIAP2 Antikörper (ABIN5700348) detektiert spezifisch BAIAP2 in WB, ELISA, IHC und IP. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für BAIAP2 Antikörper (ABIN5700348)

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAIAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-BAIAP2 Antikörper

Verwendungszweck: BAIAP2 antibody

Immunogen: BAI1-associated protein 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00793( BAIAP2 Antibody) at dilution of 1:600

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu BAIAP2

Target: BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))

Andere Bezeichnung: BAIAP2

Hintergrund:

Synonyms: Brain-specific angiogenesis inhibitor 1-associated protein 2 (BAI-associated protein 2, BAI1-associated protein 2, Protein BAP2)|Fas ligand-associated factor 3 (FLAF3)|Insulin receptor substrate p53/p58 (IRS-58, IRSp53/58)|Insulin receptor substrate protein of 53 kDa (IRSp53, Insulin receptor substrate p53)|BAIAP2

Background: The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gen-ID: 10458

UniProt: Q9UQB8