BACE1 Antikörper (AA 150-457)
Kurzübersicht für BACE1 Antikörper (AA 150-457) (ABIN5700343)
Target
Alle BACE1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 150-457
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Verwendungszweck
- BACE1 antibody
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Immunogen
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Immunogen sequence: 150-457aa
Immunogen: beta-site APP-cleaving enzyme 1
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab00781(BACE1 antibody) at dilution of 1:500
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze / thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- -20°C for 12 months
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Haltbarkeit
- 12 months
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- BACE1 (Beta-secretase 1 (BACE1))
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Andere Bezeichnung
- BACE1
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Hintergrund
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Synonyms: Beta-secretase 1|Aspartyl protease 2 (ASP2, Asp 2)|Beta-site amyloid precursor protein cleaving enzyme 1 (Beta-site APP cleaving enzyme 1)|Memapsin-2|Membrane-associated aspartic protease 2|BACE1|BACE|KIAA1149
Background: Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
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Molekulargewicht
- 70-75 kDa
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Gen-ID
- 23621
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UniProt
- P56817
Target
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