SKAP2 Antikörper

Produktnummer ABIN5699946

Dieses Anti-SKAP2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SKAP2 in WB, ELISA, IHC und IP. Geeignet für Human, Maus und Ratte.

Kurzübersicht für SKAP2 Antikörper (ABIN5699946)

Target: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKAP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-SKAP2 Antikörper

Immunogen: src kinase associated phosphoprotein 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

human liver tissue were subjected to SDS PAGE followed by western blot with FNab07890(SKAP2 antibody) at dilution of 1:1500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu SKAP2

Target: SKAP2 (Src Kinase Associated Phosphoprotein 2 (SKAP2))

Andere Bezeichnung: SKAP2

Hintergrund: Synonyms:PRAP, RA70, SAPS, SCAP2, SKAP55R Background:The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gen-ID: 8935

UniProt: O75563