MYLK Antikörper

Produktnummer ABIN5699678

Der Kaninchen Polyklonal Anti-MYLK-Antikörper wurde für WB, ELISA und IF validiert. Er ist geeignet, MYLK in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für MYLK Antikörper (ABIN5699678)

Target: MYLK (Myosin Light Chain Kinase (MYLK))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYLK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-MYLK Antikörper

Verwendungszweck: MYLK antibody

Immunogen: myosin light chain kinase

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu MYLK

Target: MYLK (Myosin Light Chain Kinase (MYLK))

Andere Bezeichnung: MYLK

Hintergrund:

Synonyms: Myosin light chain kinase, smooth muscle (MLCK, smMLCK)|Kinase-related protein (KRP)|Telokin|Myosin light chain kinase, smooth muscle, deglutamylated form|MYLK|MLCK|MLCK1|MYLK1

Background: This gene, a muscle member of the immunoglobulin gene superfamily, encodes myosin light chain kinase which is a calcium/calmodulin dependent enzyme. This kinase phosphorylates myosin regulatory light chains to facilitate myosin interaction with actin filaments to produce contractile activity. This gene encodes both smooth muscle and nonmuscle isoforms. In addition, using a separate promoter in an intron in the 3' region, it encodes telokin, a small protein identical in sequence to the C-terminus of myosin light chain kinase, that is independently expressed in smooth muscle and functions to stabilize unphosphorylated myosin filaments. A pseudogene is located on the p arm of chromosome 3. Four transcript variants that produce four isoforms of the calcium/calmodulin dependent enzyme have been identified as well as two transcripts that produce two isoforms of telokin. Additional variants have been identified but lack full length transcripts.

Molekulargewicht: 135 kDa

Gen-ID: 4638

UniProt: Q15746