ICAM1 Antikörper

Produktnummer ABIN5699217

Dieses Anti-ICAM1-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von ICAM1 in WB, FACS, IHC und ELISA. Geeignet für Human und Ratte.

Kurzübersicht für ICAM1 Antikörper (ABIN5699217)

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Reaktivität: Human, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ICAM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA

Produktdetails anti-ICAM1 Antikörper

Immunogen: intercellular adhesion molecule 1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Raji cells were subjected to SDS PAGE followed by western blot with FNab04103( ICAM-1 Antibody) at dilution of 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu ICAM1

Target: ICAM1 (Intercellular Adhesion Molecule 1 (ICAM1))

Andere Bezeichnung: ICAM-1

Hintergrund: Synonyms:BB2, CD54, ICAM 1, ICAM1, ICAM-1, P3.58 Background:ICAM-1 (CD54) is a 90- kDa transmembrane glycoprotein of the immunoglobulin superfamily and is critical for the firm attachment and transmigration of leukocytes out of blood vessels and into tissues (PMID: 19307690). ICAM-1 is expressed by several cell types, typically on endothelial cells and cells of the immune system, and its expression can be up-regulated by various stimuli, including TNF-α, INF-γ, IL-1 and thrombin (PMID: 3086451, 9694714, 15979056). It is a ligand for LFA-1 and Mac-1, serves as a receptor for rhinovirus, and is one of several receptors used by Plasmodium falciparum (PMID: 2566624, 2538244, 2475784).

Molekulargewicht: 85-95 kDa

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Regulation of Leukocyte Mediated Immunity, Thromboxane A2 Receptor Signaling