Dieses Anti-SECISBP2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SECISBP2 in WB, ELISA, IF und IP. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN5698377
Kurzübersicht für SECISBP2 Antikörper (ABIN5698377)
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freeze / thaw cycles.
Lagerung
-20 °C
Haltbarkeit
12 months
Target
SECISBP2
(SECIS Binding Protein 2 (SECISBP2))
Andere Bezeichnung
SECISBP2
Hintergrund
Synonyms:SBP2 Background:The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. The gene described in this record encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. Alternate splicing results in multiple transcript variants.