CREM Antikörper

Produktnummer ABIN5697220

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CREM in WB, ELISA, IHC und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für CREM Antikörper (ABIN5697220)

Target: CREM (CAMP Responsive Element Modulator (CREM))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CREM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-CREM Antikörper

Immunogen: cAMP responsive element modulator

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

rat testis tissue were subjected to SDS PAGE followed by western blot with FNab01970( CREM Antibody) at dilution of 1:300

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu CREM

Target: CREM (CAMP Responsive Element Modulator (CREM))

Andere Bezeichnung: CREM

Hintergrund: Synonyms:CREM, hCREM 2, ICER, Inducible cAMP early repressor Background:Transcriptional regulator that binds the cAMP response element(CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation(PubMed:10373550). Isoform 6: May play a role in the regulation of the circadian clock: acts as a transcriptional repressor of the core circadian component PER1 by directly binding to cAMP response elements in its promoter.

Molekulargewicht: 38 kDa

Gen-ID: 1390

UniProt: Q03060

Pathways: Retinoic Acid Receptor Signaling Pathway