BMP2 Antikörper (AA 283-396)

Produktnummer ABIN5697155

Der Kaninchen Polyklonal Anti-BMP2-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, BMP2 in Proben von Human, Maus, Ratte und Schwein zu detektieren.

Kurzübersicht für BMP2 Antikörper (AA 283-396) (ABIN5697155)

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-BMP2 Antikörper

Bindungsspezifität: AA 283-396

Verwendungszweck: BMP2 antibody

Immunogen:

Immunogen sequence: 283-396aa

Immunogen: bone morphogenetic protein 2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1: 5000,IHC: 1:20-1:200,IF: 1:50-1:500

Kommentare:

HeLa cells were subjected to SDS PAGE followed by western blot with FNab00917(BMP2 antibody) at dilution of 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: -20°C for 12 months

Haltbarkeit: 12 months

Details zu BMP2

Target: BMP2 (Bone Morphogenetic Protein 2 (BMP2))

Andere Bezeichnung: BMP2

Hintergrund:

Synonyms: Bone morphogenetic protein 2 (BMP-2)|Bone morphogenetic protein 2A (BMP-2A)|BMP2|BMP2A

Background: Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer, 2 monomers then associate to form the active 30 kDa homodimer, which binds to its receptor. There is also a 40-45 kDa form of BMP2, as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction.

Molekulargewicht: 45 kDa

Gen-ID: 650

UniProt: P12643

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Growth Factor Binding, Positive Regulation of fat Cell Differentiation