Asialoglycoprotein Receptor 1 Antikörper

Produktnummer ABIN5697103

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Asialoglycoprotein Receptor 1 in WB, ELISA, IHC und IP. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für Asialoglycoprotein Receptor 1 Antikörper (ABIN5697103)

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Asialoglycoprotein Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Produktdetails anti-Asialoglycoprotein Receptor 1 Antikörper

Immunogen: asialoglycoprotein receptor 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB : 1:200-1:2000 IP :1:200-1:2000 IHC : 1:50-1:500

Kommentare:

human liver tissue were subjected to SDS PAGE followed by western blot with FNab00635(ASGR1 antibody) at dilution of 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol  pH 7.3

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze / thaw cycles.

Lagerung: -20 °C

Haltbarkeit: 12 months

Details zu Asialoglycoprotein Receptor 1

Target: Asialoglycoprotein Receptor 1 (ASGR1)

Andere Bezeichnung: ASGR1

Hintergrund: Synonyms:ASGP R 1, ASGPR, ASGPR 1, Asgpr1, ASGR1, asialoglycoprotein receptor 1, CLEC4H1, Hepatic lectin H1, HL 1, Hs.12056 Background:This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molekulargewicht: 40 kDa

Gen-ID: 432

UniProt: P07306

Pathways: Thyroid Hormone Synthesis