GRM2 Antikörper (Internal Region)

Produktnummer ABIN569585

Der Ziege Polyklonal anti-GRM2 Antikörper wird verwendet zum Nachweis von GRM2 in Proben von Human, Ratte, Maus, Rind (Kuh), Hund und Kaninchen. Er wurde validiert für WB, IHC (p) und EIA.

Kurzübersicht für GRM2 Antikörper (Internal Region) (ABIN569585)

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Hund, Kaninchen

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser GRM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-GRM2 Antikörper

Bindungsspezifität: Internal Region

Sequenz: C-KETAPERREV

Spezifität: This antibody is expected to recognize both isoforms of GRM2 (NP_000830.2 and NP_001123535.1).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine, Rabbit.
Species reactivity (tested):Human.

Aufreinigung: Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide

Immunogen: Peptide with sequence from the internal region of Human GRM2 (NP_000830.2, NP_001123535.1). Genename: GRM2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GRM2

Target: GRM2 (Glutamate Receptor, Metabotropic 2 (GRM2))

Andere Bezeichnung: mGluR2 / GRM2

Hintergrund: The Metabotropic Glutamate Receptor GRM2 binds L-glutamate and has been linked to the inhibition of the cyclic AMP signaling cascade. GRM2 is involved in mediating the suppression of neurotransmission and in synaptogenesis and synaptic stabilization. Glutamatergic neurotransmission plays a role in most aspects of normal brain function and can be perturbed in many neuropathologic conditions.Synonyms: GPRC1B, Metabotropic glutamate receptor 2

Gen-ID: 2912

NCBI Accession: NP_000830

UniProt: Q14416

Pathways: cAMP Metabolic Process, Dicarboxylic Acid Transport