RPGR Antikörper (AA 13-338)

Produktnummer ABIN5693297

Produktdetails anti-RPGR Antikörper

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Bindungsspezifität: AA 13-338

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPGR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for RPGR detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human RPGR recombinant protein (Position: A13-F338).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu RPGR

Target: RPGR (Retinitis Pigmentosa GTPase Regulator (RPGR))

Andere Bezeichnung: RPGR (RPGR Produkte)

Synonyme: xrpgr antikoerper, COD1 antikoerper, CORDX1 antikoerper, CRD antikoerper, PCDX antikoerper, RP15 antikoerper, RP3 antikoerper, XLRP3 antikoerper, orf15 antikoerper, Rp3h antikoerper, retinitis pigmentosa GTPase regulator antikoerper, retinitis pigmentosa GTPase regulator S homeolog antikoerper, Rpgr antikoerper, RPGR antikoerper, rpgr antikoerper, rpgr.S antikoerper, Bm1_19935 antikoerper, NAEGRDRAFT_80250 antikoerper

Hintergrund:

Synonyms: X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3, XLRP3

Tissue Specificity: Heart, brain, placenta, lung, liver, muscle, kidney, retina, pancreas and fetal retinal pigment epithelium. Isoform 3 is found only in the retina. Colocalizes with RPGRIP1 in the outer segment of rod photoreceptors and cone outer segments.

Background: X-linked retinitis pigmentosa GTPase regulator is a GTPase-binding protein that in humans is encoded by the RPGR gene. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

UniProt: Q92834