SLK Antikörper (AA 1-232) (DyLight 488)

Produktnummer ABIN7354651

Der Kaninchen Polyklonal Anti-SLK-Antikörper wurde für FACS validiert. Er ist geeignet, SLK in Proben von Human zu detektieren.

Kurzübersicht für SLK Antikörper (AA 1-232) (DyLight 488) (ABIN7354651)

Target: SLK (STE20-Like Kinase (SLK))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLK Antikörper ist konjugiert mit DyLight 488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SLK Antikörper (DyLight 488)

Bindungsspezifität: AA 1-232

Verwendungszweck: Anti-Human SLK DyLight® 488 conjugated Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Human SLK DyLight® 488 conjugated Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Immunogen: E. coli-derived human SLK recombinant protein (Position: M1-E232).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. "Entrez Gene: SLK STE20-like kinase (yeast)". 2. Sabourin, L. A., Tamai, K., Seale, P., Wagner, J., Rudnicki, M. A. Caspase 3 cleavage of the Ste20-related kinase SLK releases and activates an apoptosis-inducing kinase domain and an actin-disassembling region. Molec. Cell. Biol. 20: 684-696, 2000. Note: Erratum: Molec. Cell. Biol. 20: 2949, 2000. 3. Zhapparova, O. N., Fokin, A. I., Vorobyeva, N. E., Bryantseva, S. A., Nadezhdina, E. S. Ste20-like protein kinase SLK (LOSK) regulates microtubule organization by targeting dynactin to the centrosome. Molec. Biol. Cell 24: 3205-3214, 2013. [

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Details zu SLK

Target: SLK (STE20-Like Kinase (SLK))

Andere Bezeichnung: SLK

Hintergrund:

Synonyms: STE20-like serine/threonine-protein kinase, STE20-like kinase, hSLK, CTCL tumor antigen se20-9, STE20-related serine/threonine-protein kinase, STE20-related kinase, Serine/threonine-protein kinase 2, SLK, KIAA0204, STK2

Tissue Specificity: Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.

Background: STE20-like serine/threonine-protein kinase is an enzyme that in humans is encoded by the SLK gene. This gene is mapped to chromosome 10q24.33-q25.1. SLK is a kinase with multiple functional domains that is predicted to regulate cytoskeletal organization and responses to apoptotic stimuli.

Molekulargewicht: 39 kDa

Gen-ID: 9748

UniProt: Q9H2G2