CD81 Antikörper (AA 113-201) (DyLight 488)

Produktnummer ABIN7354595

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD81 in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CD81 Antikörper (AA 113-201) (DyLight 488) (ABIN7354595)

Target: CD81

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD81 Antikörper ist konjugiert mit DyLight 488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CD81 Antikörper (DyLight 488)

Bindungsspezifität: AA 113-201

Verwendungszweck: Anti-Human TAPA1 DyLight® 488 conjugated CD81 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Human TAPA1 DyLight® 488 conjugated CD81 Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Immunogen: E. coli-derived human TAPA1 recombinant protein (Position: F113-K201).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. Andria ML, Hsieh CL, Oren R, Francke U, Levy S (August 1991)."Genomic organization and chromosomal localization of the TAPA-1 gene".Journal of Immunology. 147 (3): 1030-6. 2. Levy S, Todd SC, Maecker HT (1998). "CD81 (TAPA-1): a molecule involved in signal transduction and cell adhesion in the immune system.".Annu Rev Immunol. 16: 89-109.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Details zu CD81

Target: CD81

Andere Bezeichnung: CD81

Hintergrund:

Synonyms: CD81 antigen, 26 kDa cell surface protein TAPA-1, Target of the antiproliferative antibody 1, Tetraspanin-28, Tspan-28, CD81, CD81, TAPA1, TSPAN28

Tissue Specificity: Hematolymphoid, neuroectodermal and mesenchymal tumor cell lines.

Background: CD81 Molecule, also known as CD81 (Cluster of Differentiation 81), is a protein which in humans is encoded by the CD81 gene. The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. This protein appears to promote muscle cell fusion and support myotube maintenance. Also it may be involved in signal transduction. This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 39 kDa

Gen-ID: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C