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CD8 alpha Antikörper (AA 28-196)

CD8A Reaktivität: Maus, Ratte FACS, IHC, WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5693154
  • Target Alle CD8 alpha (CD8A) Antikörper anzeigen
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Bindungsspezifität
    • 16
    • 13
    • 12
    • 10
    • 9
    • 9
    • 9
    • 9
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-196
    Reaktivität
    • 233
    • 129
    • 57
    • 46
    • 13
    • 7
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 195
    • 150
    • 106
    • 3
    • 2
    Kaninchen
    Klonalität
    • 337
    • 113
    • 3
    Polyklonal
    Konjugat
    • 172
    • 50
    • 31
    • 30
    • 29
    • 9
    • 9
    • 8
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD8 alpha Antikörper ist unkonjugiert
    Applikation
    • 334
    • 154
    • 125
    • 92
    • 70
    • 63
    • 40
    • 36
    • 21
    • 15
    • 14
    • 12
    • 11
    • 9
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Western Blotting (WB), ELISA
    Verwendungszweck
    Anti-CD8 alpha/Cd8a Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-CD8 alpha/Cd8a Antibody Picoband® (ABIN5693154). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Immunogen
    E. coli-derived mouse CD8 alpha recombinant protein (Position: K28-Y196).
    Isotyp
    IgG
    Top Product
    Discover our top product CD8A Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    ELISA, 0.1-0.5 μg/mL
    1. Bowcock, A. M., Kavathas, P., Margolskee, R. F., Herzenberg, L., Cavalli-Sforza, L. L. An RFLP associated with pcDLeu2-14, a human T-cell differentiation antigen CD8 (Leu2) cDNA mapped to 2p12. Nucleic Acids Res. 14: 7817 only, 1986. 2. "Entrez Gene: CD8A CD8a molecule".
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Xu, Tan, Wang, Wang, Li, Wu, Chen, Wu, Tan: "Elevated survivin expression in peripheral blood mononuclear cells is central to collateral formation in coronary chronic total occlusion." in: International journal of molecular medicine, Vol. 35, Issue 6, pp. 1501-10, (2015) (PubMed).

    Zhang, Chen, Lao, Huang: "Effect of Hejie decoction on T cell immune state of chronic hepatitis B patients." in: World journal of gastroenterology, Vol. 10, Issue 10, pp. 1436-9, (2005) (PubMed).

  • Target
    CD8 alpha (CD8A) (CD8a Molecule (CD8A))
    Andere Bezeichnung
    Cd8a (CD8A Produkte)
    Hintergrund

    Synonyms: T-cell surface glycoprotein CD8 alpha chain, T-cell surface glycoprotein Lyt-2, CD8a, Cd8a, Lyt-2, Lyt2

    Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. It is mapped to 2p11.2. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene also encodes the CD8 alpha chain isoforms.

    Molekulargewicht
    36 kDa
    Gen-ID
    12525
    UniProt
    P01731
    Pathways
    T-Zell Rezeptor Signalweg
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