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Glutathione Reductase Antikörper (AA 256-522)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Glutathione Reductase in WB, ELISA, IF, ICC, IHC (p) und FACS. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.
Produktnummer ABIN5693151

Kurzübersicht für Glutathione Reductase Antikörper (AA 256-522) (ABIN5693151)

Target

Alle Glutathione Reductase (GSR) Antikörper anzeigen
Glutathione Reductase (GSR)

Reaktivität

  • 57
  • 28
  • 23
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Ratte, Maus

Wirt

  • 74
  • 10
Kaninchen

Klonalität

  • 72
  • 12
Polyklonal

Konjugat

  • 40
  • 5
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Glutathione Reductase Antikörper ist unkonjugiert

Applikation

  • 54
  • 26
  • 26
  • 24
  • 23
  • 16
  • 12
  • 12
  • 11
  • 10
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 15
    • 15
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 256-522

    Verwendungszweck

    Anti-Glutathione Reductase/GSR Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross reactivity with other proteins.

    Produktmerkmale

    Anti-Glutathione Reductase/GSR Antibody Picoband® (ABIN5693151). Tested in ELISA, Flow Cytometry, IF, IHC-P, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Immunogen

    E. coli-derived human Glutathione Reductase recombinant protein (Position: K256-R522).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
    Immunocytochemistry/Immunofluorescence, 5 μg/mL
    Flow Cytometry(Fixed), 1-3 μg/1x106 cells
    ELISA, 0.1-0.5 μg/mL
    1. Deponte M (May 2013). "Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes". Biochim. Biophys. Acta. 1830 (5): 3217-66. 2. Meister A (November 1988). "Glutathione metabolism and its selective modification". J. Biol. Chem. 263 (33): 17205-8.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    Glutathione Reductase (GSR)

    Andere Bezeichnung

    GSR

    Hintergrund

    Synonyms: Glutathione reductase, mitochondrial, GR, GRase, GSR, GLUR, GRD1

    Tissue Specificity: Expressed in peripheral blood leukocytes.

    Background: Glutathione reductase (GR), also known as glutathione-disulfide reductase (GSR), is an enzyme that in humans is encoded by the GSR gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

    Molekulargewicht

    52 kDa

    Gen-ID

    2936

    UniProt

    P00390

    Pathways

    Thyroid Hormone Synthesis, Cell RedoxHomeostasis
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