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Glutathione Reductase Antikörper (AA 256-522)

GSR Reaktivität: Human, Ratte, Maus WB, ELISA, IF, ICC, IHC (p), FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5693151
  • Target Alle Glutathione Reductase (GSR) Antikörper anzeigen
    Glutathione Reductase (GSR)
    Bindungsspezifität
    • 15
    • 14
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 256-522
    Reaktivität
    • 51
    • 26
    • 20
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 70
    • 5
    Kaninchen
    Klonalität
    • 68
    • 7
    Polyklonal
    Konjugat
    • 32
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Glutathione Reductase Antikörper ist unkonjugiert
    Applikation
    • 46
    • 25
    • 25
    • 22
    • 16
    • 15
    • 12
    • 10
    • 8
    • 8
    • 6
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Verwendungszweck
    Anti-Glutathione Reductase/GSR Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Anti-Glutathione Reductase/GSR Antibody Picoband® (ABIN5693151). Tested in ELISA, Flow Cytometry, IF, IHC-P, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Immunogen
    E. coli-derived human Glutathione Reductase recombinant protein (Position: K256-R522).
    Isotyp
    IgG
    Top Product
    Discover our top product GSR Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL
    Immunocytochemistry/Immunofluorescence, 5 μg/mL
    Flow Cytometry(Fixed), 1-3 μg/1x106 cells
    ELISA, 0.1-0.5 μg/mL
    1. Deponte M (May 2013). "Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes". Biochim. Biophys. Acta. 1830 (5): 3217-66. 2. Meister A (November 1988). "Glutathione metabolism and its selective modification". J. Biol. Chem. 263 (33): 17205-8.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    Glutathione Reductase (GSR)
    Andere Bezeichnung
    GSR (GSR Produkte)
    Hintergrund

    Synonyms: Glutathione reductase, mitochondrial, GR, GRase, GSR, GLUR, GRD1

    Tissue Specificity: Expressed in peripheral blood leukocytes.

    Background: Glutathione reductase (GR), also known as glutathione-disulfide reductase (GSR), is an enzyme that in humans is encoded by the GSR gene. This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found.

    Molekulargewicht
    52 kDa
    Gen-ID
    2936
    UniProt
    P00390
    Pathways
    Thyroid Hormone Synthesis, Cell RedoxHomeostasis
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