HGD Antikörper (AA 374-445)

Produktnummer ABIN5693116

Der Kaninchen Polyklonal Anti-HGD-Antikörper wurde für WB, IHC, ELISA, ICC, IF und FACS validiert. Er ist geeignet, HGD in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für HGD Antikörper (AA 374-445) (ABIN5693116)

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HGD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-HGD Antikörper

Bindungsspezifität: AA 374-445

Verwendungszweck: Anti-HGD Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-HGD Antibody Picoband® (ABIN5693116). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived human HGD recombinant protein (Position: D374-N445).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot,0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section),0.5-1 μg/mL
Immunocytochemistry/Immunofluorescence, 5 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells
ELISA,0.1-0.5 μg/mL
1. Fernandez-Canon, J. M., Granadino, B., Beltran-Valero de Bernabe, D., Renedo, M., Fernandez-Ruiz, E., Penalva, M. A., Rodriguez de Cordoba, S. The molecular basis of alkaptonuria. Nature Genet. 14: 19-24, 1996. 2. Vilboux, T., Kayser, M., Introne, W., Suwannarat, P., Bernardini, I., Fischer, R., O'Brien, K., Kleta, R., Huizing, M., Gahl, W. A. Mutation spectrum of homogentisic acid oxidase (HGD) in alkaptonuria. Hum. Mutat. 30: 1611-1619, 2009.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu HGD

Target: HGD (Homogentisate 1,2-Dioxygenase (HGD))

Andere Bezeichnung: HGD

Hintergrund:

Synonyms: Homogentisate 1,2-dioxygenase, Homogentisate oxygenase, Homogentisic acid oxidase, Homogentisicase, HGD, HGO

Tissue Specificity: Highest expression in the prostate, small intestine, colon, kidney and liver.

Background: The HGD gene encodes homogentisate 1,2-dioxygenase (HGD), an enzyme involved in the catabolism of phenylalanine and tyrosine. This enzyme is involved in the catabolism of the amino acids tyrosine and phenylalanine. Mutations in this gene are the cause of the autosomal recessive metabolism disorder alkaptonuria. This gene is mapped to chromosome 3q21-q23 by a preliminary PCR screen of hamster/human somatic cell hybrid genomic DNA samples and by fluorescence in situ hybridization.

Molekulargewicht: 50 kDa

Gen-ID: 3081

UniProt: Q93099