Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

GNS Antikörper (AA 238-355)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GNS in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN5693115

Kurzübersicht für GNS Antikörper (AA 238-355) (ABIN5693115)

Target

Alle GNS Antikörper anzeigen
GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

Reaktivität

  • 32
  • 7
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 29
  • 3
  • 1
Kaninchen

Klonalität

  • 32
  • 1
Polyklonal

Konjugat

  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser GNS Antikörper ist unkonjugiert

Applikation

  • 16
  • 13
  • 13
  • 10
  • 6
  • 5
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 238-355

    Verwendungszweck

    Anti-GNS Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-GNS Antibody Picoband® (ABIN5693115). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Immunogen

    E. coli-derived human GNS recombinant protein (Position: W238-R355).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL
    ELISA, 0.1-0.5 μg/mL
    1. "Entrez Gene: Glucosamine (N-acetyl)-6-sulfatase". 2. Basner R, Kresse H, von Figura K (February 1979). "N-Acetylglucosamine-6-sulfate sulfatase from human urine". J. Biol. Chem. 254 (4): 1151-8. 3. Kresse H, Fuchs W, Glössl J, Holtfrerich D, Gilberg W (December 1981). "N-acetylglucosamine-6-sulfate by human β-N-acetylhexosaminidase A". J. Biol. Chem. 256 (24): 12926-32.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

    Andere Bezeichnung

    GNS

    Hintergrund

    Synonyms: N-acetylglucosamine-6-sulfatase, Glucosamine-6-sulfatase, G6S, GNS

    Tissue Specificity: Found only in peripheral nervous system Schwann cells.

    Background: N-acetylglucosamine-6-sulfatase, also known as glucosamine (N-acetyl)-6-sulfatase, is an enzyme that in humans is encoded by the GNS gene. The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

    Molekulargewicht

    90 kDa

    Gen-ID

    2799

    UniProt

    P15586

    Pathways

    Glycosaminoglycan Metabolic Process
Sie sind hier:
Chat with us!