SATB1 Antikörper (AA 638-763) (DyLight 488)

Produktnummer ABIN7354604

Der Kaninchen Polyklonal Anti-SATB1-Antikörper wurde für FACS validiert. Er ist geeignet, SATB1 in Proben von Human zu detektieren.

Kurzübersicht für SATB1 Antikörper (AA 638-763) (DyLight 488) (ABIN7354604)

Target: SATB1 (SATB Homeobox 1 (SATB1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SATB1 Antikörper ist konjugiert mit DyLight 488

Applikation: Flow Cytometry (FACS)

Produktdetails anti-SATB1 Antikörper (DyLight 488)

Bindungsspezifität: AA 638-763

Verwendungszweck: Anti-Human SATB1 DyLight® 488 conjugated Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Human SATB1 DyLight® 488 conjugated Antibody -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Immunogen: E. coli-derived human SATB1 recombinant protein (Position: D638-D763).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells1. Galande S, Purbey PK, Notani D, Kumar PP (Oct 2007). "The third dimension of gene regulation: organization of dynamic chromatin loopscape by SATB1". Current Opinion in Genetics & Development. 17 (5): 408-14. 2. Pavan Kumar P, Purbey PK, Sinha CK, Notani D, Limaye A, Jayani RS, Galande S (Apr 2006). "Phosphorylation of SATB1, a global gene regulator, acts as a molecular switch regulating its transcriptional activity in vivo". Molecular Cell. 22 (2): 231-43.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Details zu SATB1

Target: SATB1 (SATB Homeobox 1 (SATB1))

Andere Bezeichnung: SATB1

Hintergrund:

Synonyms: DNA-binding protein SATB1, Special AT-rich sequence-binding protein 1, SATB1

Tissue Specificity: Expressed predominantly in thymus.

Background: The cannabinoid receptor type 1, often abbreviated as CB1, is a G protein-coupled cannabinoid receptor located primarily in the central and peripheral nervous system. This gene encodes one of two cannabinoid receptors. The cannabinoids, principally delta-9-tetrahydrocannabinol and synthetic analogs, are psychoactive ingredients of marijuana. The cannabinoid receptors are members of the guanine-nucleotide-binding protein (G-protein) coupled receptor family, which inhibit adenylate cyclase activity in a dose-dependent, stereoselective and pertussis toxin-sensitive manner. The two receptors have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. Multiple transcript variants encoding two different protein isoforms have been described for this gene.

Molekulargewicht: 39 kDa

Gen-ID: 6304

UniProt: Q01826

Pathways: Caspase Kaskade in der Apoptose, Activated T Cell Proliferation