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SPR Antikörper (AA 36-261)

Der Kaninchen Polyklonal Anti-SPR-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, SPR in Proben von Human und Maus zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN5692972

Kurzübersicht für SPR Antikörper (AA 36-261) (ABIN5692972)

Target

Alle SPR Antikörper anzeigen
SPR (Sepiapterin Reductase (SPR))

Reaktivität

  • 57
  • 29
  • 18
  • 3
  • 1
  • 1
  • 1
Human, Maus

Wirt

  • 47
  • 13
Kaninchen

Klonalität

  • 50
  • 10
Polyklonal

Konjugat

  • 33
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SPR Antikörper ist unkonjugiert

Applikation

  • 53
  • 17
  • 13
  • 13
  • 13
  • 12
  • 10
  • 6
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 15
    • 8
    • 8
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 36-261

    Verwendungszweck

    Anti-SPR Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-SPR Antibody Picoband® (ABIN5692972). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Immunogen

    E. coli-derived human SPR recombinant protein (Position: V36-K261).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot,0.1-0.5 μg/mL
    ELISA,0.1-0.5 μg/mL
    1. "Entrez Gene: SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)". 2. Ichinose H, Katoh S, Sueoka T, Titani K, Fujita K, Nagatsu T (Oct 1991). "Cloning and sequencing of cDNA encoding human sepiapterin reductase--an enzyme involved in tetrahydrobiopterin biosynthesis". Biochem Biophys Res Commun. 179 (1): 183-189. 3. Persson B, Kallberg Y, Bray JE, Bruford E, Dellaporta SL, Favia AD, Duarte RG, Jornvall H, Kavanagh KL, Kedishvili N, Kisiela M, Maser E, Mindnich R, Orchard S, Penning TM, Thornton JM, Adamski J, Oppermann U (Feb 2009). "The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative". Chem Biol Interact. 178 (1-3): 94-98.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Hu, Wang, Rao, Zhao, Yang, Hu, He, Xia, Liu, Zhen, Di, Xie, Xia, Zhu: "Alterations in the endometrium of rats, rabbits, and Macaca mulatta that received an implantation of copper/low-density polyethylene nanocomposite." in: International journal of nanomedicine, Vol. 9, pp. 1127-38, (2015) (PubMed).

  • Target

    SPR (Sepiapterin Reductase (SPR))

    Andere Bezeichnung

    SPR

    Hintergrund

    Synonyms: Sepiapterin reductase, SPR, SPR

    Background: Sepiapterin reductase is an enzyme that in humans is encoded by the SPR gene. This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.

    Molekulargewicht

    28 kDa

    Gen-ID

    6697

    UniProt

    P35270

    Pathways

    Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour, Smooth Muscle Cell Migration
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