IL-27 Antikörper (AA 29-234)

Produktnummer ABIN5692968

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IL-27 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für IL-27 Antikörper (AA 29-234) (ABIN5692968)

Target: IL-27 (IL27) (Interleukin 27 (IL27))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-27 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IL-27 Antikörper

Bindungsspezifität: AA 29-234

Verwendungszweck: Anti-IL27 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-IL27 Antibody Picoband® (ABIN5692968). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: E. coli-derived mouse IL27 recombinant protein (Position: F29-S234).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot,0.1-0.5 μg/mL
ELISA,0.1-0.5 μg/mL
1. Meka, Rakeshchandra R., Venkatesha, Shivaprasad H., Dudics, Steven, Acharya, Bodhraj, Moudgil, Kamal D. "IL-27-induced modulation of autoimmunity and its therapeutic potential". Autoimmunity Reviews. 14 (12): 1131-1141. 2. Yoshimoto, Takayuki, Chiba, Yukino, Furusawa, Jun-Ichi, Xu, Mingli, Tsunoda, Ren, Higuchi, Kaname, Mizoguchi, Izuru (2015-09-01). "Potential clinical application of interleukin-27 as an antitumor agent". Cancer Science. 106 (9): 1103-1110.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu IL-27

Target: IL-27 (IL27) (Interleukin 27 (IL27))

Andere Bezeichnung: Il27

Hintergrund:

Synonyms: Interleukin-27 subunit alpha, IL-27 subunit alpha, IL-27-A, IL27-A, p28, Il27, Il27a

Tissue Specificity: Expressed in macrophages and dendritic cells.

Background: Interleukin 27 (IL-27) is a member of the IL-12 cytokine family. The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4 (+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4 (+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Molekulargewicht: 29 kDa

Gen-ID: 246779

UniProt: Q8K3I6