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S100A7 Antikörper (AA 2-101)

Dieses Anti-S100A7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von S100A7 in WB, IHC, ELISA, ICC, FACS und IF. Geeignet für Human, Maus und Ratte.
Produktnummer ABIN5692925

Kurzübersicht für S100A7 Antikörper (AA 2-101) (ABIN5692925)

Target

Alle S100A7 Antikörper anzeigen
S100A7 (S100 Calcium Binding Protein A7 (S100A7))

Reaktivität

  • 57
  • 9
  • 4
  • 3
Human, Maus, Ratte

Wirt

  • 48
  • 17
  • 2
Kaninchen

Klonalität

  • 53
  • 14
Polyklonal

Konjugat

  • 41
  • 8
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser S100A7 Antikörper ist unkonjugiert

Applikation

  • 46
  • 29
  • 21
  • 14
  • 13
  • 13
  • 10
  • 10
  • 7
  • 6
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF)
  • Bindungsspezifität

    • 16
    • 16
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-101

    Verwendungszweck

    Anti-Psoriasin/S100A7 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Psoriasin/A7 Antibody Picoband® (ABIN5692925). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Immunogen

    E. coli-derived human Psoriasin recombinant protein (Position: S2-Q101).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
    Immunocytochemistry/Immunofluorescence, 2 μg/mL
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells
    ELISA, 0.1-0.5 μg/mL
    1. "Entrez Gene: S100A7 S100 calcium binding protein A7". 2. Winston J, Wolf R (September 2012). "Psoriasin (S100A7) promotes migration of a squamous carcinoma cell line". J. Dermatol. Sci. 67 (3): 205-7.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    S100A7 (S100 Calcium Binding Protein A7 (S100A7))

    Andere Bezeichnung

    S100A7

    Hintergrund

    Synonyms: Protein S100-A7,Psoriasin,S100 calcium-binding protein A7,S100A7,PSOR1, S100A7C,

    Tissue Specificity: Fetal ear, skin, and tongue and human cell lines. Highly up-regulated in psoriatic epidermis. Also highly expressed in the urine of bladder squamous cell carcinoma (SCC) bearing patients. .

    Background: S100 calcium-binding protein A7 (S100A7), also known as psoriasin, is a protein that in humans is encoded by the S100A7 gene. The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities.

    Molekulargewicht

    17 kDa

    Gen-ID

    6278

    UniProt

    P31151

    Pathways

    S100 Proteine
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