Neuromedin U Antikörper

Produktnummer ABIN5692905

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Neuromedin U in WB. Er zeigt eine Reaktivität gegenüber Ratte und Maus.

Kurzübersicht für Neuromedin U Antikörper (ABIN5692905)

Target: Neuromedin U (NMU)

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Neuromedin U Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Neuromedin U Antikörper

Verwendungszweck: Anti-NMU Antibody Picoband®

Sequenz: FRVDEEFQSP FASQSRGYFL FRPRN

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Homologie: Human

Produktmerkmale: Anti-NMU Antibody Picoband® (ABIN5692905). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human NMU, which shares 64% and 56% amino acid (aa) sequence identity with mouse and rat NMU, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.5 μg/mL
1. Austin, C., Lo, G., Nandha, K. A., Meleagros, L., Bloom, S. R. Cloning and characterization of the cDNA encoding the human neuromedin U (NmU) precursor: NmU expression in the human gastrointestinal tract. J. Molec. Endocr. 14: 157-169, 1995. 2. Howard, A. D., Wang, R., Pong, S.-S., Mellin, T. N., Strack, A., Guan, X.-M., Zeng, Z., Williams, D. L., Jr., Feighner, S. D., Nunes, C. N., Murphy, B., Stair, J. N., and 13 others. Identification of receptors for neuromedin U and its role in feeding. Nature 406: 70-74, 2000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu Neuromedin U

Target: Neuromedin U (NMU)

Andere Bezeichnung: NMU

Hintergrund:

Synonyms: Neuromedin-U, Neuromedin-U-25, NmU-25, NMU

Tissue Specificity: Expressed throughout the enteric nervous system with highest levels being found in the jejunum.

Background: Neuromedin U (NMU) is a neuropeptide with potent activity on smooth muscle, which was isolated first from porcine spinal cord and later from other species. It is a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.

Molekulargewicht: 26 kDa

Gen-ID: 10874

UniProt: P48645

Pathways: Feeding Behaviour, Photoperiodism