Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Laminin gamma 1 Antikörper (all Isoforms)

Dieses Anti-Laminin gamma 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Laminin gamma 1 in WB, IHC und IF. Geeignet für Human, Maus und Ratte. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
Produktnummer ABIN5692889

Kurzübersicht für Laminin gamma 1 Antikörper (all Isoforms) (ABIN5692889)

Target

Alle Laminin gamma 1 (LAMC1) Antikörper anzeigen
Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

Reaktivität

  • 48
  • 25
  • 20
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 44
  • 9
  • 5
Kaninchen

Klonalität

  • 42
  • 16
Polyklonal

Konjugat

  • 41
  • 6
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Laminin gamma 1 Antikörper ist unkonjugiert

Applikation

  • 37
  • 29
  • 17
  • 14
  • 11
  • 9
  • 8
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    all Isoforms

    Verwendungszweck

    Anti-Laminin/Lamc1/Lamc2/Lamc3 Antibody Picoband®

    Sequenz

    NKLNEIEGSL NKAKDEMKAS ,DLEERVRRQR NHLHLLETSI ,LQLDSHGALH HKLRQLEEES

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Laminin/Lamc1/Lamc2/Lamc3 Antibody Picoband® (ABIN5692889). Tested in IF, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    Peptide mixture of laminin gamma1,2,3 (NKLNEIEGSLNKAKDEMKAS, DLEERVRRQRNHLHLLETSI, LQLDSHGALHHKLRQLEEES). Laminin gamma has only three subtypes of antibody to gamma1-3 reactive with all isoforms of laminin.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat,
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
    Immunofluorescence, 2 μg/mL, Mouse, Rat
    1. Aumailley M et al. (2005). "A simplified laminin nomenclature". Matrix Biol. 24 (5): 326-32. 2. Colognato H, Yurchenco P (2000). "Form and function: the laminin family of heterotrimers".Dev. Dyn. 218 (2): 213-34. 3. Timpl R et al. (1979). "Laminin - a glycoprotein from basement membranes". J Biol Chem 254 (19): 9933-7.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Fu, Hu, Dang, Chang, Du, Wu, Gao: "Remarkable preservation of Ca(2+) homeostasis and inhibition of apoptosis contribute to anti-muscle atrophy effect in hibernating Daurian ground squirrels." in: Scientific reports, Vol. 6, pp. 27020, (2018) (PubMed).

    Chen, Wang, Liu, Fang, Tan, Zhou, Zhou, Lv: "Highly effective ex vivo gene manipulation to study kidney development using self-complementary adenoassociated viruses." in: TheScientificWorldJournal, Vol. 2014, pp. 682189, (2014) (PubMed).

  • Target

    Laminin gamma 1 (LAMC1) (Laminin, gamma 1 (LAMC1))

    Andere Bezeichnung

    Lamc1

    Hintergrund

    Synonyms: Laminin subunit gamma-1,Laminin B2 chain,Laminin-1 subunit gamma,Laminin-10 subunit gamma,Laminin-11 subunit gamma,Laminin-2 subunit gamma,Laminin-3 subunit gamma,Laminin-4 subunit gamma,Laminin-6 subunit gamma,Laminin-7 subunit gamma,Laminin-8 subunit gamma,Laminin-9 subunit gamma,S-laminin subunit gamma,S-LAM gamma,Lamc1,Lamb-2, Lamc-1,

    Tissue Specificity: Found in the basement membranes (major component).

    Background: Tumor necrosis factor ligand superfamily member 14 is a protein that in humans is encoded by the TNFSF14 gene. TNFSF14 has also been designated as CD258, as well as LIGHT. It was mapped on chromosome 19p13.3. The protein encoded by this gene is a member of the tumor necrosis factor(TNF) ligand family. This protein may function as a costimulatory factor for the activation of lymphoid cells and as a deterrent to infection by herpesvirus. It has been shown to stimulate the proliferation of T cells, and trigger apoptosis of various tumor cells. This protein is also reported to prevent tumor necrosis factor alpha mediated apoptosis in primary hepatocyte. Two alternatively spliced transcript variant encoding distinct isoforms have been reported.

    Molekulargewicht

    150, 220-250 kDa

    Gen-ID

    226519

    UniProt

    P02468
Sie sind hier:
Chat with us!