HMBS Antikörper (AA 6-361)

Produktnummer ABIN5692868

Produktdetails anti-HMBS Antikörper

Target: HMBS (Hydroxymethylbilane Synthase (HMBS))

Bindungsspezifität: AA 6-361

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMBS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for HMBS detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human HMBS recombinant protein (Position: N6-H361).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot,0.1-0.5 μg/mL
Direct ELISA,0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu HMBS

Target: HMBS (Hydroxymethylbilane Synthase (HMBS))

Andere Bezeichnung: HMBS (HMBS Produkte)

Synonyme: PBG-D antikoerper, PBGD antikoerper, PORC antikoerper, UPS antikoerper, URO-S antikoerper, hemC antikoerper, pbg-d antikoerper, pbgd antikoerper, ups antikoerper, SPAC806.01 antikoerper, DDBDRAFT_0186148 antikoerper, DDBDRAFT_0231417 antikoerper, DDB_0186148 antikoerper, DDB_0231417 antikoerper, Hmbs antikoerper, NV50236 antikoerper, T25658 antikoerper, Ups antikoerper, Uros1 antikoerper, hmbs antikoerper, zgc:64128 antikoerper, hmbsl antikoerper, id:ibd5004 antikoerper, im:7140060 antikoerper, zgc:110690 antikoerper, hydroxymethylbilane synthase antikoerper, hydroxymethylbilane synthase S homeolog antikoerper, hydroxymethylbilane synthase L homeolog antikoerper, hydroxymethylbilane synthase (predicted) antikoerper, Hydroxymethylbilane synthase antikoerper, hydroxymethylbilane synthase a antikoerper, hydroxymethylbilane synthase, b antikoerper, HMBS antikoerper, Hmbs antikoerper, hmbs antikoerper, hmbs.2.S antikoerper, hmbs.L antikoerper, CNC02250 antikoerper, hem3 antikoerper, hemC antikoerper, Trad_0335 antikoerper, Plabr_2100 antikoerper, Sgly_3113 antikoerper, SMLT_RS19660 antikoerper, PMI_RS16580 antikoerper, hmbsa antikoerper, hmbsb antikoerper

Hintergrund:

Synonyms: Porphobilinogen deaminase, PBG-D, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase, HMBS, PBGD, UPS

Tissue Specificity: Isoform 1 is ubiquitously expressed. Isoform 2 is found only in erythroid cells.

Background: Porphobilinogen deaminase (hydroxymethylbilane synthase, or uroporphyrinogen I synthase) is an enzyme that in humans is encoded by the HMBS gene. This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

UniProt: P08397