HMBS Antikörper (AA 6-361)

Produktnummer ABIN5692868

Dieser Anti-HMBS Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von HMBS in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für HMBS Antikörper (AA 6-361) (ABIN5692868)

Target: HMBS (Hydroxymethylbilane Synthase (HMBS))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMBS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HMBS Antikörper

Bindungsspezifität: AA 6-361

Verwendungszweck: Anti-HMBS Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-HMBS Antibody (ABIN5692868). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived human HMBS recombinant protein (Position: N6-H361).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot,0.1-0.5 μg/mL, Human, Mouse, Rat
ELISA,0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu HMBS

Target: HMBS (Hydroxymethylbilane Synthase (HMBS))

Andere Bezeichnung: HMBS

Hintergrund:

Synonyms: Porphobilinogen deaminase, PBG-D, Hydroxymethylbilane synthase, HMBS, Pre-uroporphyrinogen synthase, HMBS, PBGD, UPS

Tissue Specificity: Isoform 1 is ubiquitously expressed. Isoform 2 is found only in erythroid cells.

Background: Porphobilinogen deaminase (hydroxymethylbilane synthase, or uroporphyrinogen I synthase) is an enzyme that in humans is encoded by the HMBS gene. This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

Molekulargewicht: 45 kDa

Gen-ID: 3145

UniProt: P08397