Topoisomerase I Antikörper (AA 526-765)
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- Target Alle Topoisomerase I (TOP1) Antikörper anzeigen
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
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Bindungsspezifität
- AA 526-765
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Topoisomerase I Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
- Rabbit IgG polyclonal antibody for Topoisomerase I detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.
- Immunogen
- E. coli-derived human Topoisomerase I recombinant protein (Position: E526-F765).
- Top Product
- Discover our top product TOP1 Primärantikörper
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- Applikationshinweise
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Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.
Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg NaN3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
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- Target
- Topoisomerase I (TOP1) (Topoisomerase (DNA) I (TOP1))
- Andere Bezeichnung
- TOP1 (TOP1 Produkte)
- Substanzklasse
- Viral Protein
- Hintergrund
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Synonyms: DNA topoisomerase 1, DNA topoisomerase I, TOP1,
Tissue Specificity: Endothelial cells.
Background: DNA topoisomerase 1 is an enzyme that in humans is encoded by the TOP1 gene. This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
- UniProt
- P11387
- Pathways
- Caspase Kaskade in der Apoptose, Stem Cell Maintenance
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