Cullin 4A Antikörper (AA 494-759)

Produktnummer ABIN5692838

Produktdetails anti-Cullin 4A Antikörper

Target: Cullin 4A (CUL4A)

Bindungsspezifität: AA 494-759

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cullin 4A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Marke: Picoband™

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Cullin 4a detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Immunogen: E. coli-derived human Cullin 4a recombinant protein (Position: M494-A759).

Anwendungsinformationen

Applikationshinweise:

Recommended Detection Systems: Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ABIN921124) for Western blot.

Application Details: Western blot, 0.1-0.5 μg/mL
Direct ELISA, 0.1-0.5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na₂HPO₄, 0.05 mg NaN₃.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.

Details zu Cullin 4A

Target: Cullin 4A (CUL4A)

Andere Bezeichnung: CUL4A (CUL4A Produkte)

Synonyme: zgc:64071 antikoerper, CUL4A antikoerper, 2810470J21Rik antikoerper, AW495282 antikoerper, RGD1563853 antikoerper, cullin 4A antikoerper, CUL4A antikoerper, cul4a antikoerper, Cul4a antikoerper

Hintergrund:

Synonyms: Cullin-4A, CUL-4A, CUL4A

Background: Cullin-4A is a protein that in humans is encoded by the CUL4A gene. It belongs to the cullin family of ubiquitin ligase proteins and is highly homologous to the CUL4B protein. CUL4A regulates numerous key processes such as DNA repair, chromatin remodeling, spermatogenesis, haematopoiesis and the mitotic cell cycle. As a result, CUL4A has been implicated in several cancers and the pathogenesis of certain viruses including HIV. Interestingly, a component of a CUL4A complex, Cereblon, was discovered to be a major target of the teratogenic agent thalidomide.

UniProt: Q13619