ULK4 Antikörper (AA 1120-1170)

Produktnummer ABIN5690313

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch ULK4 in WB, ELISA, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für ULK4 Antikörper (AA 1120-1170) (ABIN5690313)

Target: ULK4 (ULK24) (Unc-51-Like Kinase 4 (ULK24))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ULK4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ULK4 Antikörper

Bindungsspezifität: AA 1120-1170

Spezifität: ULK4 antibody is human and mouse reactive. Multiple isoforms of ULK4 are known to exist.

Aufreinigung: ULK4 antibody is affinity chromatography purified via peptide column.

Immunogen: ULK4 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human ULK4.

The immunogen is located within amino acids 1120 - 1170 of ULK4.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ULK4 antibody can be used for detection of ULK4 by Western blot at 0.5 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL. For immunofluorescence start at 20 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: ULK4 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: ULK4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu ULK4

Target: ULK4 (ULK24) (Unc-51-Like Kinase 4 (ULK24))

Andere Bezeichnung: ULK4

Hintergrund: ULK4 belongs to the Ser/Thr protein kinase superfamily and plays a role in the ATP-dependent phosphorylation of target proteins (1). Knockout of ULK genes results in a severe defect in the autophagy pathway (2). ULK4, like the other Unc-51-like kinases such as ULK1, ULK2 and ULK3, is highly conserved among eukaryotes (3). ULK4 has been implicated as a gene involved in the development of hydrocephalus (3). This neurologic disorder is being used in animal models to elucidate factors responsible for the excessive accumulation of cerebrospinal fluid in hydrocephalic humans (4).

Molekulargewicht: Predicted: 140 kDa

Observed: 165 kDa

Gen-ID: 54986

NCBI Accession: NP_060356

UniProt: Q96C45